The Lightning Project

The ongoing saga of the PNG Lightning Maroon Clownfish Breeding Project

Browsing Posts tagged Erythromycin

Popeye Update

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Just a quick update as I’ve simply not had time to take pictures, nor get the permissions I’ve asked for.  In a nutshell, once again, we *may* have adverted a crisis.  I’ve been consulting a fish vet for the past few days, and for lack of a better way of explaining it, there are lots of things a vet would want to do to a fish in this condition that aren’t practical.  Not practical in so much as the vet I’ve been talking with is 3 hours away, and can’t be here on site to see the fish even if I could afford to compensate the vet for the trip and time combined.  The other practical issue is one of risk and probabilities; netting a fish with an infected eye is never a good idea, and as I learned, a swab of the eye would likely yield no pathogens anyways as the causative agent is probably largely internal.  Plus, if there is an ongoing infection of the eye itself, I could easily see a swab somehow popping the eye and well, making matters worse.  In the end, it is my opinion that while consulting with a vet made for a very good sounding board and gave me some new things to consider, without the direct interaction, there was little if anything different the vet would’ve had me do.  Plus, considering I was seeing some improvements as we were consulting, it’s difficult for any doctor to suggest a change if what’s being done outwardly appears to be working.  I get that, 100%.  And on the topic of prevention – minimize stress, maximize good water quality. No surprise, I’ve been doing that for years.  So I think none of us have even a guess as to why this is happening, which means that every hypothesis we’ve put forth could be valid.

So yesterday (Tuesday) was the last dose in the 5 day course of Maracyn and Maracyn II, which I ran only weeks prior for the mouth rot.  I’ve been feeding the Dr. G’s food daily; I’ve made this judgement call to feed at twice the package’s recommendation based on several things, but perhaps most importantly that the Lightning Maroon isn’t an aggressive feeder (never really has been) and thus, it’s difficult to get this fish to eat as much as  you might think it should within a 1-minute time window (as prescribed by the food’s directions).  Still, it’s important to note that this food introduces both Metronidozole and Kanamycin to the mix, and it is again reef safe as far as I can tell.

The downside here is that the Lightning Maroon’s interest in food was diminished today, so getting a fish to eat the medicated food is obviously a problem.  The pair however, has been cleaning like crazy…for all I know the pair could wind up spawning (my female Percula often has a diminished appetite in the day or tow prior to a spawn).

The actual eye – much improved and it would seem that there isn’t any vision loss.  There is still some tissue bulging out around the eye however, which made me reluctant to stop the treatment with Erythromycin and Monocycline (active ingredients of Maracyn and Maracyn II).  I’m trusting the vet on this one.

Here’s the real worry, and sadly this does make some sense.  Mycobacteriosus.  Both the female Maroon I first had so many problems with, and then the Morse-Code Maroon, basically shared similar afflictions (pop eye and mouth rot respectively) that I have encountered in none of my other marine fish.  Yes, that’s it.  NEVER.  I cannot recall ever having popeye in another marine fish here, and certainly not mouth rot.  So why would 3 out of 6 PNG Maroons be the only fish in my entire household to ever wind up with these diseases?  Well, it’s much more understandable if we view this as a pathogen that they were all exposed to before they came to me.  We know that Mycobacterium can lay dormant in fish for a long time, which could also explain why the Lightning Maroon has gone this long without issues.  If it IS Mycobacterium behind the external and recurring symptoms I’m seeing, well, that could be *it* for the Lightning Maroon no matter what I do.  It’s a very harsh theory to even consider, and even more alarming given that the theory happens to explain a whole heck of a lot of the issues I’d had, let alone also possibly explaining why these problems are isolated to a small group of fish from one species from one location, where half of them have had semi-common symptoms.

For now, please just send all those positive vibes.  The tank got a 10 gallon water change today, and hopefully the Lightning Maroon remains on the road to recovery.  Let’s get several more good years with her if we can.

I believe I shot these Sunday AM.

 

It is now Monday AM, and honestly, things are improving.  The appetite of the Lightning Maroon remains strong, which I’ve used to ensure that it continues to feed on the Dr. G’s antibacterial formula.  I should preface this by saying that the Lightning Maroon has always been a timid feeder, so food generally has to flow right by its face / into its territory for it to feed.  So I’m definitely not following the Dr. G. feeding protocol (as much as they can eat in one minute, every other day).

In talking with the man behind Dr. G’s feeds, the feeds are set up to roughly deliver a “minimum effective dose”.  In the case of the anti-parasite Dr. G. formulation (which is laced with Chloroquin Posphate), you can quadruple the feeding regime (twice per day vs. once every other day) and have no ill-effects on the fish (although the Dr. doesn’t recommend that).  Knowing how most every antibiotic is normally delivered, it honestly doesn’t make sense to dose every-other day via feed, so I’m going to feed the food once per day to maintain antibiotic levels.  It’s worth mentioning that the active ingredients in the Dr. G formula are Kanamycin and Metronidozole.

All in all, this means that I have no less than 4 antibiotics running around.  I’ve been talking with two fish vets who I’ll refrain from naming for the time being.  One has of course, expressed concern over the “shotgun” approach, understandably so.  For me, I’m thinking that the repeat of the Maracyn & Maracyn II are probably of little efficacy, but they were what I had on hand to immediately address the problem.  Still, I am more likely to credit the Dr. G’s as the moment, if only because positive progress only started being made once it was introduced to the regime starting on Saturday evening.  Still, it could be the other medications.

The main goal here is twofold – #1. effectively cure this latest round of garbage.  #2. figure out WHY it’s happening soas to prevent it.  As of Monday AM, the eye looks better (less white stuff), so maybe we will get through this latest bout again.  But I’m fully wondering what the heck is causing the fish to break down repeatedly.  Mechanical damage? Food?

Or could we even be looking at an old-age, immuno-compromized fish?  Afterall, they DON’T live forever, they are NOT immortal.  Could it simply be that the Lightning Maroon is an older fish, nearing it’s time, and all my drastic measures are simply staving off the inevitable?  I hope not.

Despite all this, the male is cleaning the tile like crazy.

 

Friday, April 27, 2012.

I’ll keep this short and bittersweet. In the last 24 hours the Lightning Maroon has developed a pretty rapid spreading case of what appears to be mouth rot. You may recall a similar situation occurring with the Morse-Code Maroon, and that did not end well.

The biggest question is WTF – or more appropriately, WHY?! Did I introduce a pathogen from the Onyx Percula tank? It’s possible, but that group of fish has been disease free for who knows how long, and would qualify to be every bit as QT’d as the Lightning Maroon. PLUS, the Four Eye Butterflyfish that they reside with was taken from the Onyx Perc’s tank originally. So odds are that there was nothing new introduced.

Does it have something to do with the eggs? Could be. Could be that eating fungused eggs exposed the fish to elevated bacterial / fungal levels which in turn has led to infection. Or it could be the tile surface is somehow abrading the lips as they clean, and again opening a pathway to infection.

Or could it be something more sinister? If I’m blunt, perhaps the pop-eye I saw earlier on was not in fact a “bruise”, cauesed by mechanical damage, but was in fact an early warning sign for infection. If I really read some of the symptoms listed out, it actually sounds like a disease called Ichthyophonus hoferi, which is an internal fungal infection, with the exception being that the Lightning Maroon is not exhibiting any of the erratic behavioral symptoms.

However, this disease does most closely match the symptoms of classic mouth-rot, which is treatable with Erythromycin (one of the rarer ones). In fact, you can pick up a package of Maracyn SW and pretty much it deals with all of these symptoms. I keep it on hand, and I’ve found it to be very reef-safe, so without hesitation, I removed the carbon and dosed the tank today with the first dose of Maracyn SW. As of this evening, I have seen no improvement, and in fact, it does appear that the Lightning Maroon lost it’s appetite tonight. This is NOT GOOD.

I am toying with the notion of removing the egg tile. I’m looking at the Aiptasia in their vicinity and wondering if I need to eradicate those as well (haven’t caused any problems before, so why would they now…but maybe I still should). I am thinking of hitting both the Gram Positive AND Gram Negatives by including Maracyn II SW (Maracyn hits Gram Positive infections). I’m thinking about moving the fish into a well established QT tank. The options are endless, but it’s a situation like this where I hate being the fish vet, because the long-standing hobbyist in me has not seen a tremendous success rate in treating these types of infections. Of course, in the last 7 years, there has been only one other fish to have this issue…and that was another PNG Maroon. What are the odds?

All fish will die, that’s a given fact. But damnit, I will be really bummed if this is how the story of the Lightning Maroon comes to pass. And yeah, I’m really going WTF…this is the type of disease that really just should never happen in a clean, well maintained system. WTF?!

Saturday, April 28th

I half expected to wake up to a dead Lightning Maroon, but it wasn’t. It’s appetite was “not great”. So one of the big questions here is how to turn this around. I started medicating with Maracyn SW yesterday, but that only treats gram-positive bacterial infections. While the symptoms match up well with the symptoms of diseases Maracyn is supposed to treat, would it actually work?

And so, I embarked on a search for the companion product, Maracyn II SW. The active ingredient is Monocycline. I was 30 minutes into a 6 hour round trip to the only store in the Twin Cities that had the medication on hand (Ocean Devotion), when I got a call back from local reefer Frank Wotruba saying he had it on-hand. Shortly therafter, Jay Hansen also called saying he had it on hand. This is a great example of the benefits of being am actively participating member of a marine aquarium club.

I picked up a package of Maracyn II SW from Frank, and headed home. I had put in a call to Sentry AQ, the current manufacturers of Mardel aquarium medications, as I wanted to confirm that I could use Maracyn SW in conjunction with Maracyn II SW. The woman who I spoke with was kind, if not helpful, as the fish guy was out to lunch. I never did get a call back despite leaving my information, but later I found an acceptable answer on the website:

“Yes, Mardel Maracyn can be used in conjunction with almost all Mardel fish medications. The only exception would be Maracyn Plus. (We do not recommend using another antibiotic with Maracyn Plus.)”

This means that the two can be conjoined, and so, without delay, I added in the first dosage of Maracyn II for marine fish to the Lightning Maroon’s tank.  I think we’re looking at a pretty strong case to be made that both these anti-biotics are completely reef safe…although your water will glow yellow with the blue lighting.

Sunday, April 29th, 2012

Once again I woke up expecting to find a dead Lightning Maroon. The spread of the mouth rot seems to have stopped, but there is definitely necrotic tissue breakdown happening. It is possible that even if I save the fish, it will loose at minimum the upper right maxillary. Thankfully that’s not a problem for a fish; they actually use maxillary clips in young salmonids to help with strain and year class identification in hatchery fish. Still, outwardly, things do not look any BETTER. Yes, I have contemplated surgery.

Knowing that Maracyn II SW treats gram negative bacteria, and knowing that will more likely impact biological filtration, I did a 10 gallon water change around noon.  The Onyx Perc eggs hatched overnight, and the fish overall are ignoring the tile.  I did use some Tropic Marin ElimAptasia to knock back the larger anemones…while the fish might be protected, I wonder if the infected area is getting stung by the Aiptasia and screwing up the healing process.  After this work, I dosed with both Maracyn SW and Maracyn II SW. So this is day 3 for Erythromycin, and day 2 for Monocycline.  And yes, looking back at the Morse Code Maroon now, I know I switched to this combination of medications after Kanamycin failed to give me any results.  If I am dealing with an internal fungal infection, particular the type that can be introduced through the feeding of raw fish (I have no clue what foods, if any that I have, contain raw fish), there is little I can do as far as my reading suggests.  Still, I may have to switch here and go to a hospital tank if what I’m doing at this point fails to work.  Yes, I am thinking of plan B now.

I truly have no clue how this will all turn out, and I am beyond frustrated. That said, I’m also completely confident that I’m doing the best I can with the materials I have, so there’s no burden of guilt here. Solely the stress of fighting off what could be the end of a 2 year effort to breed this magnificent fish.

Today was just a crazy day.  A week in the making, I owe a bit of thanks to Jonica and her husband Scott (rest of her name withheld for privacy).  They provided the impetus for a day long road trip from Duluth to the Twin Cities region to pick up another massive female Maroon Clownfish.  This one happens to be a Gold Stripe Maroon (Sumatran form).  She’s pretty darn big, although the “Labrador” female from Frank & Mary has at least another 2 inches on her!  Thanks for this great donation to the cause.  She’ll have a good home here!

As you may know, the *plan* for whatever big female I could find was to place her on the other side of the eggcrate with the “Morse Code” Maroon in the hopes of applying social pressure to test the sexuality of the Morse Code maroon, and hopefully keep it a male if it still could be a Male.

Let me say now that the Morse Code Maroon continues to decline despite being hit with both Maracyn and Maracyn Two in combination.  So I’ve now thrown three antibiotics at this problem with no resolution.  It’s a slow progressing infection, but frankly, I hate to see fish suffer for so long.  Here’s where things looked tonight when I got home.

Now, I must say that I’m toying with swabbing that with Hydrogen Peroxide.  At this point, what else can I really do?!

Meanwhile, there is no way, and arguably no point, to introduce the new female Gold Stripe Maroon on the other side of the divider.  The Morse Code is lethargic to the point where social pressure isn’t going to do a darn thing for it.  There’s no positive upside at the moment to risking the GSM, so instead, she was placed into one of the QT Tanks with one of the smallest 3 PNG Maroons.  Submission was instantaneous on the part of the little Maroon, so it is safe to say that at minimum, this one small PNG Maroon will remain male until called upon for service!

IF by some crazy chance this pair happened to spawn, I may opt to rear the babies solely for practice, but all of them would be humanely euthanized.  This may sound very cruel, but the reality is that such offspring are possible “hybrids” (there has been talk in the past that the Gold Stripe Maroon could be reclassified as a different species).  Regardless, they would be a mixing of color variants / races, which for all intents and purposes is something fish breeders should strive to avoid.  Afterall, I could hypothesize that the resultant offspring could turn out like either parent, or more likely a muddled version of a GSM.  And the reality is they wouldn’t be discernible by the average hobbyist or even most breeders.  In other words, there is NO upside to releasing such a fish into the hobby.  So yes, they would be put down.  But at least I would get some valuable experience rearing Premnas larvae.  Long term though, this temporary pairing will be split up, and each fish ultimately placed with an appropriate mate.

Meanwhile, I finally found the time to do a bit of eggcrate and zip tie fabrication.  The Lightning Maroon has been given a larger, more spacious home with a better view and the ability to better interact with the Labrador Maroon.  If they couldn’t see each other before, now they can.  The new eggcrate cage is pretty substantial.  I’ve heard stories, I think one told to me by Carl Kmiec, of clownfish being able to fertilize a spawn even when separated by eggcrate, even several inches away.  Could that happen in this situation?  Who knows?!

New larger "egg crate" breeder net!

Hinged top opens to provide easy access. Used the frame from an old breeder net to provide easy hangers.

The Lightning Maroon Clownfish chilling in his deflated bubble tip anemones.

One more top down view of the Lightning Maroon chlling in its RBTA!

That’s going to be it for tonight!  Catch you tomorrow!

So as it stands, the Morse Code Maroon Clown, the largest one that was shipped, got Maracyn SW last night after a 50% water change.  That seems to have had no affect.  So tonight, lacking guidance and having a bit of desperation based on the ever-declining health of this fish, I doubled down and added in Maracyn II SW.  Mardel’s medications often suggest using combinations, but as it turns out, reading the details, there is never a discussion of using these two particular medications together.  I’m running out of options on this fish, and it appears the fish is running out of time.

The second largest PNG Maroon shipped has shown signs of a mild Brooklynella infection.  I hit the tank housing him with Formalin on Wed. night, and now again Friday night.  The nice thing is that after the first treatment, his appetite returned.

The remaining 3, all the smallest, have shown no symptoms of disease.  They all feed well and behave normally.  The same goes for the smaller PNG Saddlebacks that I was also shipped this time around.  I believe these observations lend further anecdotal evidence to the notion that if you’re going to buy wild caught clownfish, smaller, younger fish tend to suffer less in transit and prove more resilient.  And frankly, wanting smaller clowns is probably a better way to go when talking about wild caught fish.  Afterall, the juvenile clownfish harvested from the reef is not a large breeder, producing the future generations.  So when it comes to sustainability, it makes sense to pursue juveniles for a myriad of reasons.

The Lightning Maroon, the star of our show, remains awesome as always.

A Morse Code Update

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- …. .   — — .-. … .   -.-. — -.. .   — .- .-. — — -.   .. …   …. .- -. –. .. -. –.   .. -.   – …. . .-. . –..–   -… ..- -   – .- .-.. -.-   .- -… — ..- -   .- -. — – …. . .-.   .-.. . … … — -.   .. -.   .–. .- – .. . -. -.-. .   .- -. -..   ..-. .-. ..- … – .-. .- – .. — -.

OK, seriously though, the rest of the post will be in plain English ;)

I’ve discussed the problems facing the “Morse Code” Maroon with Christine Williams and Boomer.  Both often make a reference of Edward Noga.  As you know, I’ve been treating the Morse Code’s mouth rot with Kanamycin.  From Christine, the dosage of Kanamycin for fish is “50-100 mg/liter every 3 days for 3 treatments with a 50% WC before each”.

As you know, I’m using Kanamycin powder from National Fish Pharmacy (www.fishyfarmacy.com).  Both Christine and Boomer have suggested that the dosage on Kanamycin may be “low” compared to that recommended by Noga.  So I sat and “did the math”.

I’m using their consumer packaged Kanamycin, which is called “Kana Pro”.  From their website, the dosage is 1/4 teaspon per 20 gallons of water.  Treat every 24 hours with a 25% water change before each treatment.  Treat for 10 days.  For tuberculosis, use for up to 30 days.

The entire package of Kana Pro is 20 grams, and treats 640 gallons at their dosage rate.  Per their dosage, that works out to 1 gram (1000 mg) treating 32 gallons of water (121 Liters).  This works out to roughly 8.25 mg per L per day.  If I went to dosing every third day at that level, it amounts to roughly 25 mg per L.  This is basically half of Noga’s minimum dosage.  Of course, I simply also need to mention that other experts give dosages lower than Noga, i.e. more in the range of 20 mg/L to 50 mg/L according to the sources that Boomer cited, but Boomer was quick to add that often times, the dosage for a medication in saltwater can be as much as twice that in freshwater.  That could easily account for a disparity between Noga and the other references, specifically if Noga is talking marine and the others were talking fresh!

So far, at best I was only at the absolute bare minimum therapeutic level for Kanamycin based on the dosage.  But then things took another bizzare turn.  Boomer noticed it, credit where credit is due.  National Fish Pharmacy sells both Kana-Pro (hobbyist packaged product) and bulk Kanamycin Sulfate powder.  20 Grams of Kana Pro sells for $14.  25 grams of bulk Kanamycin Sulfate sells for $35.  The net result – Kana Pro sells for about 50% of what the bulk product sells for.  WHY?!  Even more curious, the package of Kana Pro says right on it “Pure kanamycin sulfate powder – no inert ingredients added”.

While I have not found the time to contact National Fish Pharmacy to ask about this very peculiar discrepency, it is certainly suggestive that the hobbyist-packaged Kana Pro cannot be the same thing as the Kanamycin Sulfate that our published experts are referring to when they talk about dosages.  At best, it may be that the bulk Kanamycin Sulfate is a higher GRADE and thus more expensive.  At worst, the Kana Pro could very well be a diluted form, perhaps mandated as such by the FDA for “home use” (this is purported to be a FDA-Approved product).  In the worse case scenario, could it be that the “Kana Pro” is diluted by 50% or more (would clearly justify costing half as much!)?  The real implication, when you follow it through, is that if Kana Pro is 50% or less of the active ingredient, then the labeled dosage might not be just “half” of Noga’s minimum dosage, but 25% or lower of the minimum suggested dosage by Noga.

And we wonder why medicating fish is a “complicated” issue!  Well, after 3 doses following the instructions, I had seen no results.  Once Christine, Boomer and I had these conversations, I took it upon myself to immediately DOUBLE the volume of dosage of Kana Pro I was using.  Based on all the information I had at hand, it seemed to be a safe and likely necessary step.

On Tuesday, I took another step – I swabbed the fish.  The plan was to send a sample to Christine for culturing / identification.  Obviously, if I we can figure out what exactly is going on, we have a better chance to treat it.  If nothing else, we may be able to put a real label on these photos and say “here’s a known case of X infecting a Maroon Clownfish”.  Of course, I missed the post office, so the package went out Wed and should arrive Friday.  Obviously, answers will not be immediate.

It is now Thursday night, and for the past 3 nights I’ve been using the doubled dose of Kana Pro.  The verdict? Let the pictures tell you:

It is pretty clear to me that Kanamycin, even at the doubled dosage, is having NO affect on this infection.  My plan now has been to abandon this (as I’ve used almost an entire package with no results now).  Around 8:00 PM I placed a large back of fresh carbon in the filter.  I’ll followup with a larger partial water change as well, and probably by midnight, I’ll be using a different medication.  Looking at what I have on hand, and what has more often succeeded than failed, it will probably be Maracyn SW (Erythromycin).  I believe I also have Maracyn Two SW (Monocycline) running around.  I believe I can even tag-team these two medications by using them together, hitting both gram-positive and gram-negative bacteria respectively.  Given that Kanamycin treats gram-negative bacteria primarily, the use of Monocycline with Erythromycin may be unnecessary, but at this point, what’s a guy to do?

…is that life has a way of giving you a nice smack in the face, aka a “reality check”.  The old phrase “don’t count your [clownfish] before they hatch”  seems to apply here.

I alluded to it at the end of my last post.  Yes, the “Morse Code” Maroon is having issues…it showed signs almost immediately and 24 hours in I made the decision to move it into another empty tank and begin treatment.  Not having the benefit of a laboratory, nor the luxury of a vet, I was forced to make a rapid guess and hope I was right.  Time this weekend has been nonexistent (a visit to see my best friend who lives in DC, then a car was hit on the street, and a family member was put under and had surgery today, doing well thank you) but I’ve at least been staying on feeding and treatment regimes.  Here’s where the Morse Code Maroon went…

So what exactly is wrong with the Morse Code Maroon?  I’m not 100% sure, but I did notice what looked like “rawness” on the mouth when the fish was released.  The pictures from that evening don’t really show it.  24 hours in, the mouth had turned gray and was showing signs of erosion, and so, the fish was moved.  Here’s what I was looking at.

For the moment, I’ll just use the generic term “Mouth Rot”, which really describes only a symptom, something that could be caused by a myriad of possible vectors.  As I stated earlier, not having a lot of time to diagnose and collaborate on this one, I went with Kanamycin, which I had on hand from the “lost shipment” when I was trying to switch antibiotics on the original female PNG Maroon.  As an “shotgun approach” antibiotic, it was the recommendation of at least a couple of the project advisors earlier on.  I figured, why not?  Christine Williams and Boomer both definitely preferred it over my personal default, Erythromycin.  Seems that Kanamycin is not that easy to find, but this is the one I’m using, from FishyFarmacy.com.

Today, I have to say I’ve not seen any signs of improvement.  No, things appear to have gotten worse.  Let the pictures speak for themselves:

Add on stringy feces, decreased activity, and the possibility of Brooklynella showing up (can’t say yet) and this fish is arguably going downhill fast.  Tonight is the 4th of 5 scheduled doses of Kanamycin.  I’m going to do it, but if time permits over the next 24 hours I’m going to solicit for opinions and do the researching I can do.  Need to turn this fish around, FAST!  I have a feeling I’ll be switching medications tomorrow.

Shocked…

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…that the female Maroon is still alive this morning.  I genuinely thought she was a goner.  I could say that there is growing consensus that at this point separating the female PNG Maroon from the Lightning Maroon is a good idea.  However, this notion flies in the face of “keep things stable, avoid stress” etc.  I’ve been making preparations.

The Brine Shrimp I had hatching failed yesterday (some did hatch out, but mostly it ended up being a bacteria soup, which means that bottle of decapped is no longer “good” and it’s time to order a new one…has been here at least a year, so no fault of Dan’s).  I mentioned it to the group of Advisers.  Kent Vitamin C and Live Adult Brine Shrimp arrived from Mark Martin @ Blue Zoo Aquatics this morning – thanks for the quick shipment Mark!  I’ll get that adult brine set up in a bucket and start feeding it with Rotifer Grow Plus (from Reed Mariculture / Reef Nutrition).  Vitamin C will get dosed as the level prescribed on the bottle.  Mark made a very good point about Vitamin C.  I normally use Reef Plus for vitamins, and I had suggested that I knew I could easily and safely double the dosage of that.  Mark’s point – when you get sick,  you don’t up the dosage of all your vitamins, just the Vitamin C.  Very very true, and thus, Vitamin C on hand for direct singular dosing.

Edit - I did dose Vitamin C, 8 drops into the 20 gallon tank.  The rate is 20 drops into 50 gallons daily.  There have also been concerns about secondary infections.   Christine Williams is a proponent of Kanamycin, but I am a fan of Erythromycin in the form of Mardel’s Maracyn SW.  It has worked on a myriad of occasions.  I tried it on the other QT system in conjunction with the Formalin and it stopped the bacterial problems I had once I started dosing.  Maracyn SW is also high in B-Vitamins that stimulate appetite.  I keep Maracyn SW on hand at all times.  And I’ve never killed a fish dosing Maracyn SW.  So, the 20 long got hit with Maracyn this morning as well.

Lightning Maroon was perky this morning.  Darn female…I want them BOTH perky.

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